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SILDENAFIL - WikiVidi Documentary

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Sildenafil, sold as the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. Its effectiveness for treating sexual dysfunction in women has not been demonstrated. Common side effects include headaches and heartburn, as well as flushed skin. Caution is advised in those who have cardiovascular disease. Rare, but serious side effects include prolonged erections, which can lead to damage to the penis, and sudden-onset hearing loss. Sildenafil should not be taken by people who take nitrates such as nitroglycerin , as this may result in a severe and potentially fatal drop in blood pressure. Sildenafil acts by inhibiting cGMP-specific phosphodiesterase type 5 , an enzyme that promotes degradation of cGMP, which regulates blood flow in the penis. Pfizer scientists Andrew Bell, David Brown, and Nicholas Terrett originally discovered sildenafil as a treatment for various cardiovascular disorders. Since becoming available in... http://www.wikividi.com ____________________________________ Shortcuts to chapters: 00:01:23 Pulmonary hypertension 00:01:36 Altitude sickness 00:01:49 Adverse effects 00:02:55 Interactions 00:03:45 Recreational use 00:05:11 Jet lag research 00:05:31 Sports 00:05:44 Analogs 00:06:43 Mechanism of action 00:09:03 History 00:10:19 Marketing and sales ____________________________________ Copyright WikiVidi. Licensed under Creative Commons. Wikipedia link: https://en.wikipedia.org/wiki/Sildenafil
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